Bernhard Schaefke

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Bernhard Schaefke

Research Assistant Professor

Work Experience

2018 – present: Research Assistant Professor, Southern University of Science and Technology, Academy for Advanced Interdisciplinary Studies & Department of Biology
2017 – 2018: Senior Research Scientist, Department of Biology, SUSTech, Shenzhen


2015: Ph.D., Bioinformatics, Taiwan International Graduate Program
2006: Postgraduate Certificate in Applied Bioinformatics, ‘Cologne University BioInformatics Center’ (CUBIC)
2005: “Diplom” in Biology (equivalent to master’s degree), University of Cologne

Scientific Research

  1. Evolution of different layers of gene regulation and genetic basis of hybrid vigor and hybrid incompatibilities
  2. Comparative biology of closely related mammalian species (e.g., house mouse and Algerian mouse; humans and great apes), investigating the molecular mechanisms underlying differences in reproduction, behavior and metabolism
  3. Application of evolutionary and molecular genetic insights in biomedicine (e.g., for human reproductive health), conservation biology and animal husbandry


  • Schaefke, B., Sun, , Li, Y.S., Fang, L., and Chen, W. (2018). Evolution of Post-Transcriptional Regulation. Wiley Interdiscip Rev RNA.
  • Sun, W., Gao, Q., Schaefke, B., Hu, Y., Chen, W. (2018). Pervasive allele-specific regulation on RNA decay in hybrid mice. Life Science Alliance 1.2 (2018): e201800052. Web. 03 Sept2018
  • Schaefke, B., Wang, T.Y., Wang, C.Y., and Li, W.H. (2015). Gains and Losses of Transcription Factor Binding Sites in Saccharomyces cerevisiae and paradoxus. Genome Biol. Evol. 7(8), 2245–2257
  • Schaefke, B., Emerson, J.J., Wang, T.Y., Lu, M.Y., Hsieh, L.C., and Li, W.H. (2013). Inheritance of gene expression level and selective constraints on trans– and cis-regulatory changes in yeast. Mol. Biol. Evol. 30, 2121-2133
  • Molcanyi, M., Riess, P., Bentz, K., Maegele, M., Hescheler J., Schäfke, B., Trapp, T., Neugebauer, E., Klug, N., Schäfer, U. (2007). Trauma-associated inflammatory response impairs embryonic stem cell survival and integration after implantation into injured rat brain. J Neurotrauma.