Qionghua Zhu

Qionghua Zhu

Research Assistant Professor

Professional Experience

2020-present Research Assistant Professor, Department of biology, Southern University of Science and Technology (SUSTech)

2019-2020 Senior scientist, Department of biology, Southern University of Science and Technology (SUSTech)

2016-2019 Postdoc, Cancer Research Program, Max-Delbrück-Center for Molecular Medicine (MDC), Germany

Educational Background

2010-2016 Ph.D. (Cell Biology), MDC & Humboldt-Universität zu Berlin, Germany

2007-2010 M.Sc. (Pharmacology), Zhejiang University, Hangzhou, China

1999-2003 B.Sc. (Pharmaceutical Sciences), Zhejiang University, Hangzhou, China

Selected Publication

  1. Praktiknjo S, Obermayer B, Zhu Q, Fang L, Liu H, Quinn H, Stoeckius M, Kocks C, Birchmeier W, Rajewsky N. Tracing tumorigenesis in a solid tumor model at single-cell resolution. Nat Commun. 2020 Feb 20;11(1):991. (co-first author)
  2. Zhu Q, Fang L, Heuberger J, Kranz A, Schipper J, Scheckenbach K, Vidal RO, Sunaga-Franze DY, Müller M, Wulf-Goldenberg A, Sauer S, Birchmeier W. The Wnt-driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer. Cell reports. 2019 Jan 26: 415–
  3. Ma Y, Peng Y, Zhu Q, Gao A, Chao B, He Q, Li J, Hu Y, Zhou Y. CHOP activator LGH00168 induces necroptosis via reactive oxygen species-induced ER stress and NF-κB inhibition in A549 lung cancer cells. Acta Pharmacologica Sinica. 2016 Sep;37(10):1381-1390. (co-first author)
  4. Yi H, Li G, Long Y, Liang W, Cui H, Zhang B, Tan Y, Li Y, Shen L, Deng D, Tang Y, Mao C, Tian S, Cai Y, Zhu Q, Hu Y, Chen W, Fang L. Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT. Oncogene. 2020 Jul;39(28):5152-5164.
  5. Fang L, Zhu Q, Neuenschwander M, Specker E, Wulf-Goldenberg A, Weis WI, von Kries JP, Birchmeier W. A small-molecule antagonist of the β-catenin/TCF4 interaction blocks the self-renewal of cancer stem cells and suppresses tumorigenesis. Cancer Research. 2016 Feb 15;76(4):891-901.
  6. Wend P, Fang L, Zhu Q, Schipper JH, Loddenkemper C, Kosel F, Brinkmann V, Eckert K, Hindersin S, Holland JD, Lehr S, Kahn M, Ziebold U, Birchmeier W. Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours. EMBO J. 2013 Jul 17;32(14):1977-89.